Overview

From scattered spreadsheets to one living evidence library

Pre-discovery research starts with in-depth searches of the literature and public data repositories. Assembling that evidence is slow, and findings too often end up in separate spreadsheets with poor version control and infrequent updates.

Aevidence changes all that. Its specialized discovery apps let you explore evidence from public and internal sources, and gather, organize, update, and share it to:

Aevidence app overview
Use cases

Interactive, intuitive, inspiring

Single cell app

Single cell

A high-performance, interactive environment for exploring complex transcriptomic data, spatial data, and high-dimensional cellular maps, with lasso selection synchronized across UMAPs and tissue slides.

Structural bioinformatics

Structural bioinformatics

Visualize 3D structures and explore underlying sequences of experimentally determined and computed proteins in the RCSB protein data bank. Understanding the 3D structure of a biological macromolecule is critical for discerning its role in health, disease, and therapeutics.

Bioactivity

Bioactivity

Investigate comparative human, mouse, and rat data from ChEMBL and PROTAC-DB. Review characteristics of bioactive molecules with drug-like properties and proteolysis-targeting chimeras (PROTACs), and define target and off-target filters as well as structural constraints.

General information

General information

Retrieve a concise summary of your genes or diseases of interest and their function. For genes, the subcellular location view shows where within the cell a protein of interest is expressed. Click on a description to highlight the organelle in the cell diagram.

Protein sequence analysis

Protein sequence analysis

Retrieve protein sequence alignments between human and animal species commonly used in preclinical toxicology studies, view human gene orthologs and homologous human proteins, and run multiple sequence alignments focused on protein domains of interest.

GWAS and PheWAS studies

GWAS and PheWAS studies

Get summary statistics from internal and public genome-wide association (GWAS) and phenome-wide association (PheWAS) studies, with links to publications in PubMed, and drill down to a regional association plot for any genomic range.

Oncology

Oncology

Access a visual overview of genomic alterations documented in The Cancer Genome Atlas (TCGA): alteration prevalence by cancer type, expression in tumor and normal samples, missense mutation hotspots, gene effect scores from DepMap, and survival analyses for selected patient cohorts.

Expression analysis

Expression analysis

Compare expression of one or multiple genes using integrated data from GTEx, TCGA, and CCLE. Visualize expression in the context of tissue type, disease status, or other factors, and define cohorts using genomic markers.

Dossier app

Dossier

AI-powered reporting that turns fragmented R&D data into decision-ready dossiers, combining cited literature AI, live plots from Aevidence and Ordino, and collaborative rich text.

CRISPR base editing app

CRISPR base editing

Map and interpret gRNA spacer regions and editing outcomes across genomic coordinates, protein sequence, and 3D structure, enriched with public data from visynData.

Develop your own Aevidence app

Work with us to build an app tailored to your requirements and discovery data landscape.

Aevidence Structure analysis app with the in-app AI assistant
AI

Discover agentic visual intelligence

Human-AI collaboration across the R&D lifecycle. Aevidence works with your AI co-scientists, with rich, interactive visuals instead of text and static plots.

Shown: the Structure analysis app for EGFR, with the in-app AI assistant.

In-app intelligence & human control

An embedded in-app assistant inside Aevidence helps researchers discover features and execute workflows using natural language, keeping human expertise in full control.

Interactive apps inside enterprise agents

Standardized Model Context Protocol (MCP) layers connect datavisyn tools directly to agents like Claude and Copilot, which render fully functional, interactive visual components inside the chat window.

Verifiable & transparent decision-making

Visual audit trails and transparent decision provenance let human teams and AI co-scientists cross-check outputs and answer deep research questions together.

Aevidence 3D structure analysis shown inside Claude via MCP-app
Spotlight use case

Structure analysis app in Claude via MCP-app

Researchers query complex data in plain English, manipulate live 3D structures, and automatically sync UI actions back to the model.

  • Live embedded UI: Interactive 3D and scatter plots directly inside chat
  • Two-way state sync: Real-time UI selections steer downstream AI reasoning
  • Frictionless discovery: Connect enterprise LLMs without hitting dead ends
Explore our AI roadmap→
Demo

All the evidence you need

visynData

Integrated biomedical intelligence

Aevidence and Ordino both draw on visynData, which integrates more than 80 public sources and data repositories, including UniProt, GTEx, ChEMBL, Reactome, cBioPortal, DepMap, and TCGA. We curate and update it regularly.

Import tools make it easy to add your in-house experimental data, and we work with customers to prioritize new sources for future updates.

Explore visynData→

Get started with Aevidence

Try it out today→

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